Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0002871
Disease: Anemia
Anemia 		0.700 Therapeutic RGD We conclude that serum hepcidin levels can predict the hematologic responsiveness to erythropoiesis-stimulating agent therapy in anemia of chronic disease. 24895335

2014
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0002871
Disease: Anemia
Anemia 		0.700 Therapeutic RGD Pharmacologic inhibition of hepcidin expression results in mobilization of iron from the RES, stimulation of erythropoiesis and correction of anemia. 21730356

2011
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0002871
Disease: Anemia
Anemia 		0.700 Biomarker RGD Here the authors investigate the hepcidin-involved iron absorption in exercise-associated anemia. 21411831

2011
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.600 Biomarker RGD Through a quantitative methylation analysis on HCC tissues, we then proved that methylation at definite CpG sites within consensus sequences for specific transcription factors is possibly the mechanism underlying HAMP repression. 29235098

2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0282193
Disease: Iron Overload
Iron Overload 		0.600 Biomarker RGD Changes in serum hepcidin levels in acute iron intoxication in a rat model. 19524651

2009
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.570 Biomarker RGD Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure. 20631677

2010
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.280 Biomarker RGD Hepcidin and DNA promoter methylation in hepatocellular carcinoma. 29235098

2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5 		0.260 Biomarker RGD Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure. 20631677

2010
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.210 Therapeutic RGD Inhibiting heme oxygenase-1 attenuates rat liver fibrosis by removing iron accumulation. 23704825

2013
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.210 Biomarker RGD Hepcidin is strongly induced in cardiomyocytes under myocarditis and MI, conditions in which inflammatory cytokine levels increase and may play an important role in iron homeostasis and free radical generation. 19615879

2010
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0042842
Disease: Vitamin A Deficiency
Vitamin A Deficiency 		0.210 Biomarker RGD Vitamin A deficiency increased liver hepcidin mRNA and iron spleen concentrations; however, iron deficiency in vitamin A-deficient rats deeply inhibits liver hepcidin mRNA expression and significantly increases divalent metal transporter-1 mRNA levels. 19217259

2009
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.200 Biomarker RGD Hepcidin and DNA promoter methylation in hepatocellular carcinoma. 29235098

2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.200 Biomarker RGD Hepcidin and DNA promoter methylation in hepatocellular carcinoma. 29235098

2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C2676033
Disease: Hepatoblastoma Caused By Somatic Mutation
Hepatoblastoma Caused By Somatic Mutation 		0.200 Biomarker RGD Hepcidin and DNA promoter methylation in hepatocellular carcinoma. 29235098

2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C2750440
Disease: FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1 		0.200 Biomarker RGD Hepcidin levels correlate to liver iron content, but not steatohepatitis, in non-alcoholic fatty liver disease. 29871592

2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C2750441
Disease: LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1 		0.200 Biomarker RGD Hepcidin levels correlate to liver iron content, but not steatohepatitis, in non-alcoholic fatty liver disease. 29871592

2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C3150651
Disease: FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2 		0.200 Biomarker RGD Hepcidin levels correlate to liver iron content, but not steatohepatitis, in non-alcoholic fatty liver disease. 29871592

2018
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C2750440
Disease: FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1 		0.200 Biomarker RGD  Differences in hepatic expression of iron, inflammation and stress-related genes in patients with nonalcoholic steatohepatitis. 28051796

2017
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C2750441
Disease: LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1 		0.200 Biomarker RGD  Differences in hepatic expression of iron, inflammation and stress-related genes in patients with nonalcoholic steatohepatitis. 28051796

2017
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C3150651
Disease: FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2 		0.200 Biomarker RGD  Differences in hepatic expression of iron, inflammation and stress-related genes in patients with nonalcoholic steatohepatitis. 28051796

2017
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.200 Biomarker RGD Hepcidin is increased in the hypertrophied heart of Dahl salt-sensitive rats. 24424338

2014
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0034902
Disease: Pure Red-Cell Aplasia
Pure Red-Cell Aplasia 		0.200 Biomarker RGD Iron as the key modulator of hepcidin expression in erythroid antibody-mediated hypoplasia. 25580431

2014
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.200 Biomarker RGD Inflammatory regulation of iron metabolism during thioacetamide-induced acute liver injury in rats. 24373749

2014
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0023892
Disease: Biliary cirrhosis
Biliary cirrhosis 		0.200 Therapeutic RGD Inhibiting heme oxygenase-1 attenuates rat liver fibrosis by removing iron accumulation. 23704825

2013
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
CUI: C0029810
Disease: Other specified iron deficiency anemias
Other specified iron deficiency anemias 		0.200 Biomarker RGD Suppressed hepcidin expression correlates with hypotransferrinemia in copper-deficient rat pups but not dams. 22457245

2012