Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.380 Biomarker CTD_human Alterations in gene expression profiles during prostate cancer progression: functional correlations to tumorigenicity and down-regulation of selenoprotein-P in mouse and human tumors. 12235003

2002
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.340 Biomarker CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0001430
Disease: Adenoma
Adenoma 		0.330 Biomarker CTD_human Three SNPs located in the 3' region of SEPP1, which is overlapping with the promoter region of an antisense transcript, were significantly associated with adenoma risk: homozygotes at two SEPP1 loci (31,174 bp 3' of STP A>G and 43,881 bp 3' of STP G>A) were associated with increased adenoma risk [odds ratio (OR), 1.48; 95% confidence interval (95% CI), 1.00-2.19 and OR, 1.53; 95% CI, 1.05-2.22, respectively] and the variant SEPP1 44,321 bp 3' of STP C>T was associated with a reduced adenoma risk (CT versus CC OR, 0.85; 95% CI, 0.63-1.15). 18483336

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.320 Biomarker CTD_human Quantitative real-time reverse transcription-PCR for Selenoprotein-P demonstrated a similar down-regulation of the transcript of this gene in a subset of human prostate tumors, mouse tumors, and prostate carcinoma cell lines. 12235003

2002
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.310 Biomarker CTD_human Expression of selenoprotein-coding genes SEPP1, SEP15 and hGPX1 in non-small cell lung cancer. 19058871

2009
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0524851
Disease: Neurodegenerative Disorders
Neurodegenerative Disorders 		0.310 Biomarker CTD_human Pharmacogenomic profiling of an oxidative stress-mediated spongiform encephalopathy. 15964507

2005
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.300 Biomarker CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0014175
Disease: Endometriosis
Endometriosis 		0.300 Biomarker CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642

2011
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0269102
Disease: Endometrioma
Endometrioma 		0.300 Biomarker CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642

2011
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0006635
Disease: Cadmium poisoning
Cadmium poisoning 		0.300 Biomarker CTD_human Involvement of selenoprotein P and GPx4 gene expression in cadmium-induced testicular pathophysiology in rat. 20643113

2010
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.300 Biomarker CTD_human Expression of selenoprotein-coding genes SEPP1, SEP15 and hGPX1 in non-small cell lung cancer. 19058871

2009
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.300 Biomarker CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0021364
Disease: Male infertility
Male infertility 		0.300 Biomarker CTD_human Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice. 17961124

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.300 Biomarker CTD_human Neurodegeneration in mice resulting from loss of functional selenoprotein P or its receptor apolipoprotein E receptor 2. 18172410

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.300 Biomarker CTD_human Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice. 17961124

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0205646
Disease: Adenoma, Basal Cell
Adenoma, Basal Cell 		0.300 Biomarker CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0205647
Disease: Follicular adenoma
Follicular adenoma 		0.300 Biomarker CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0205648
Disease: Adenoma, Microcystic
Adenoma, Microcystic 		0.300 Biomarker CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0205649
Disease: Adenoma, Monomorphic
Adenoma, Monomorphic 		0.300 Biomarker CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0205650
Disease: Papillary adenoma
Papillary adenoma 		0.300 Biomarker CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0205651
Disease: Adenoma, Trabecular
Adenoma, Trabecular 		0.300 Biomarker CTD_human Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. 18483336

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0848676
Disease: Subfertility, Male
Subfertility, Male 		0.300 Biomarker CTD_human Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice. 17961124

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0917731
Disease: Male sterility
Male sterility 		0.300 Biomarker CTD_human Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice. 17961124

2008
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.300 Biomarker CTD_human Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942

2005
Entrez Id: 6414
Gene Symbol: SELENOP
SELENOP
CUI: C0024667
Disease: Animal Mammary Neoplasms
Animal Mammary Neoplasms 		0.300 Biomarker CTD_human Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942

2005