Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6580
Gene Symbol: SLC22A1
SLC22A1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Therapeutic RGD Regulation of renal organic anion and cation transporters by thymoquinone in cisplatin induced kidney injury. 22414646

2012
Entrez Id: 6580
Gene Symbol: SLC22A1
SLC22A1
CUI: C0005398
Disease: Cholestasis, Extrahepatic
Cholestasis, Extrahepatic 		0.200 Biomarker RGD Elevated systemic elimination of cimetidine in rats with acute biliary obstruction: the role of renal organic cation transporter OCT2. 20814153

2010
Entrez Id: 6580
Gene Symbol: SLC22A1
SLC22A1
CUI: C0008372
Disease: Intrahepatic Cholestasis
Intrahepatic Cholestasis 		0.200 Biomarker RGD Reduced antidiabetic effect of metformin and down-regulation of hepatic Oct1 in rats with ethynylestradiol-induced cholestasis. 19002567

2009
Entrez Id: 6580
Gene Symbol: SLC22A1
SLC22A1
CUI: C0376618
Disease: Endotoxemia
Endotoxemia 		0.200 Therapeutic RGD Nitric oxide down-regulates the expression of organic cation transporters (OCT) 1 and 2 in rat kidney during endotoxemia. 18313662

2008
Entrez Id: 6580
Gene Symbol: SLC22A1
SLC22A1
CUI: C0004096
Disease: Asthma
Asthma 		0.200 Biomarker RGD Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse. 17328924

2007
Entrez Id: 6580
Gene Symbol: SLC22A1
SLC22A1
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.200 Biomarker RGD Reduced expression of organic cation transporters rOCT1 and rOCT2 in experimental diabetes. 14718608

2004