Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.550 Biomarker CTD_human In addition, intraventricular administration of TRH, LHRH or LH caused tachycardia, hypertension and a reduction in the epinephrine-induced reflex bradycardia. 6350720

1983

Entrez Id: 7200
Gene Symbol: TRH
TRH
THYROTROPIN-RELEASING HORMONE DEFICIENCY
0.500 Biomarker CTD_human

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0036572
Disease: Seizures
Seizures
0.310 Biomarker CTD_human PRI-2191 alone had no effect on gene expression, but it enhanced the seizure-evoked expression of HSP-70, had an opposite effect on BDNF mRNA level and did not affect prepro-TRH mRNA level. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0036572
Disease: Seizures
Seizures
0.310 Biomarker CTD_human These data showed that pilocarpine- and kainate-induced seizures enhanced likewise preproTRH mRNA in the dentate gyrus; on the other hand, they differed with respect to time- and structure-related changes in TRH tissue levels and TRH receptors. 10443546

1999

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0030193
Disease: Pain
Pain
0.310 Therapeutic CTD_human Antinociceptive properties of thyrotropin releasing hormone in mice: comparison with morphine. 6409194

1983

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.300 Biomarker CTD_human Molecular evidence for differences in endometrium in severe versus mild endometriosis. 21063030

2011

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Molecular evidence for differences in endometrium in severe versus mild endometriosis. 21063030

2011

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute
0.300 Biomarker CTD_human Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias. 18206229

2008

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0026998
Disease: Acute Myeloid Leukemia, M1
Acute Myeloid Leukemia, M1
0.300 Biomarker CTD_human Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias. 18206229

2008

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C1879321
Disease: Acute Myeloid Leukemia (AML-M2)
Acute Myeloid Leukemia (AML-M2)
0.300 Biomarker CTD_human Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias. 18206229

2008

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0022333
Disease: Jacksonian Seizure
Jacksonian Seizure
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0149958
Disease: Complex partial seizures
Complex partial seizures
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0234533
Disease: Generalized seizures
Generalized seizures
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0234535
Disease: Clonic Seizures
Clonic Seizures
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0270844
Disease: Tonic Seizures
Tonic Seizures
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0270846
Disease: Epileptic drop attack
Epileptic drop attack
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0422850
Disease: Seizures, Somatosensory
Seizures, Somatosensory
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0422852
Disease: Seizures, Auditory
Seizures, Auditory
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0422853
Disease: Olfactory seizure
Olfactory seizure
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0422854
Disease: Gustatory seizure
Gustatory seizure
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0422855
Disease: Vertiginous seizure
Vertiginous seizure
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0494475
Disease: Tonic - clonic seizures
Tonic - clonic seizures
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0751056
Disease: Non-epileptic convulsion
Non-epileptic convulsion
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005

Entrez Id: 7200
Gene Symbol: TRH
TRH
CUI: C0751110
Disease: Single Seizure
Single Seizure
0.300 Biomarker CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040

2005