Source: ORPHANET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950121
Disease: Denys-Drash Syndrome
Denys-Drash Syndrome 		1.000 GermlineCausalMutation ORPHANET In ten independent cases of Denys-Drash syndrome, point mutations in the zinc finger domains of one WT1 gene copy were found. 1655284

1991
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0950122
Disease: Frasier Syndrome
Frasier Syndrome 		0.800 GermlineCausalMutation ORPHANET Gonadal tumor in Frasier syndrome: a review and classification. 25623218

2015
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0206115
Disease: WAGR Syndrome
WAGR Syndrome 		0.800 ChromosomalRearrangement ORPHANET The modifier effect of the BDNF gene in the phenotype of the WAGRO syndrome. 23266638

2013
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.800 SusceptibilityMutation ORPHANET

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.800 SomaticCausalMutation ORPHANET

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C1837026
Disease: MEACHAM SYNDROME (disorder)
MEACHAM SYNDROME (disorder) 		0.700 GermlineCausalMutation ORPHANET WT1 in disease: shifting the epithelial-mesenchymal balance. 21959952

2012
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C1837026
Disease: MEACHAM SYNDROME (disorder)
MEACHAM SYNDROME (disorder) 		0.700 GermlineCausalMutation ORPHANET WT1 mutations in Meacham syndrome suggest a coelomic mesothelial origin of the cardiac and diaphragmatic malformations. 17853480

2007
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0281508
Disease: Desmoplastic Small Round Cell Tumor
Desmoplastic Small Round Cell Tumor 		0.600 FusionGene ORPHANET

Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C1868672
Disease: NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE
NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE 		0.400 GermlineCausalMutation ORPHANET A novel WT1 gene mutation in a three-generation family with progressive isolated focal segmental glomerulosclerosis. 20150449

2010
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C0018054
Disease: Gonadal Dysgenesis, 46,XY
Gonadal Dysgenesis, 46,XY 		0.310 GeneticVariation ORPHANET WT1 mutation as a cause of 46 XY DSD and Wilm's tumour: a case report and literature review. 21314844

2011
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C4510744
Disease: 46,XY partial gonadal dysgenesis
46,XY partial gonadal dysgenesis 		0.300 GeneticVariation ORPHANET WT1 deletion leading to severe 46,XY gonadal dysgenesis, Wilms tumor and gonadoblastoma: case report. 25613702

2015
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C2931803
Disease: Deletion 11p13
Deletion 11p13 		0.300 ChromosomalRearrangement ORPHANET The modifier effect of the BDNF gene in the phenotype of the WAGRO syndrome. 23266638

2013
Entrez Id: 7490
Gene Symbol: WT1
WT1
CUI: C2936694
Disease: Swyer Syndrome
Swyer Syndrome 		0.300 GeneticVariation ORPHANET WT1 mutation as a cause of 46 XY DSD and Wilm's tumour: a case report and literature review. 21314844

2011