| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
thyroid hormone receptor alpha | 0.566 | 0.769 | 0.33 |
|
phenotype | 0.400 | strong | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
opioid receptor mu 1 | 0.457 | 0.808 | 7.9E-11 |
|
phenotype | 0.340 | None | 1.000 | 5 | 0 | 2016 | 2019 | ||||||||
|
proopiomelanocortin | 0.356 | 0.846 | 1.2E-04 |
|
phenotype | 0.310 | None | 1.000 | 2 | 0 | 1988 | 2019 | ||||||||
|
glucagon | 0.431 | 0.885 | 3.5E-02 |
|
phenotype | 0.310 | None | 1.000 | 2 | 0 | 2002 | 2020 | ||||||||
|
mediator complex subunit 13 | 0.711 | 0.538 | 1.00 |
|
phenotype | 0.300 | moderate | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
paraoxonase 1 | 0.409 | 0.885 | 9.8E-11 |
|
phenotype | 0.300 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
G protein-coupled bile acid receptor 1 | 0.548 | 0.731 | 1.4E-09 |
|
phenotype | 0.300 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
ret proto-oncogene | 0.392 | 0.885 | 1.00 |
|
phenotype | 0.130 | None | 1.000 | 3 | 1 | 2000 | 2019 | ||||||||
|
cholinergic receptor muscarinic 3 | 0.464 | 0.885 | 0.99 |
|
phenotype | 0.130 | None | 1.000 | 3 | 0 | 2016 | 2018 | ||||||||
|
glial cell derived neurotrophic factor | 0.434 | 0.885 | 0.20 |
|
phenotype | 0.130 | None | 1.000 | 3 | 0 | 2000 | 2019 | ||||||||
|
solute carrier family 6 member 3 | 0.453 | 0.885 | 1.00 |
|
phenotype | 0.120 | None | 1.000 | 2 | 0 | 2018 | 2018 | ||||||||
|
leucine rich repeat kinase 2 | 0.510 | 0.808 | 2.6E-30 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
transthyretin | 0.423 | 0.885 | 0.52 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
filamin A | 0.419 | 0.846 | 1.00 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2007 | 2007 | ||||||||
|
methyl-CpG binding protein 2 | 0.414 | 0.846 | 0.89 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
phosphofurin acidic cluster sorting protein 1 | 0.603 | 0.615 | 1.00 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
neurturin | 0.686 | 0.538 | 3.0E-02 |
|
phenotype | 0.110 | None | < 0.001 | 1 | 0 | 2002 | 2002 | ||||||||
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
KIT proto-oncogene, receptor tyrosine kinase | 0.366 | 0.808 | 0.98 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
phenotype | 0.110 | None | 1.000 | 1 | 1 | 2004 | 2004 | ||||||||
|
dopa decarboxylase | 0.535 | 0.769 | 3.8E-08 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
paired like homeobox 2B | 0.565 | 0.731 | 0.94 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
endothelin receptor type B | 0.470 | 0.846 | 9.2E-03 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 1994 | 1994 | ||||||||
|
catechol-O-methyltransferase | 0.400 | 0.923 | 1.1E-06 |
|
phenotype | 0.110 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
mitogen-activated protein kinase kinase 1 | 0.439 | 0.846 | 0.90 |
|
phenotype | 0.100 | None | 1.000 | 7 | 1 | 2006 | 2009 |