| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
plasminogen activator, urokinase | 0.425 | 0.923 | 2.3E-06 |
|
disease | 0.300 | None | 1.000 | 2 | 0 | 1996 | 2003 | ||||||||
|
complement C3 | 0.445 | 0.885 | 0.90 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 1992 | 1992 | ||||||||
|
spastin | 0.579 | 0.577 | 1.00 |
|
disease | 0.100 | None | 1.000 | 91 | 5 | 2000 | 2019 | ||||||||
|
atlastin GTPase 1 | 0.593 | 0.654 | 0.98 |
|
disease | 0.100 | None | 0.972 | 36 | 2 | 1997 | 2019 | ||||||||
|
SPG7 matrix AAA peptidase subunit, paraplegin | 0.436 | 0.885 | 2.0E-36 |
|
disease | 0.100 | None | 0.833 | 24 | 1 | 1998 | 2019 | ||||||||
|
SPG11 vesicle trafficking associated, spatacsin | 0.576 | 0.538 | 1.6E-39 |
|
disease | 0.100 | None | 1.000 | 24 | 0 | 2004 | 2019 | ||||||||
|
receptor accessory protein 1 | 0.653 | 0.423 | 0.99 |
|
disease | 0.100 | None | 1.000 | 20 | 1 | 2006 | 2019 | ||||||||
|
kinesin family member 5A | 0.593 | 0.731 | 1.00 |
|
disease | 0.100 | None | 0.941 | 17 | 1 | 2004 | 2018 | ||||||||
|
MEFV innate immuity regulator, pyrin | 0.440 | 0.885 | 1.0E-14 |
|
disease | 0.100 | None | 0.909 | 11 | 4 | 2003 | 2019 | ||||||||
|
heat shock protein 90 beta family member 2, pseudogene | 0.558 | 0.846 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 2006 | 2017 | |||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.100 | None | 0.900 | 10 | 0 | 1997 | 2018 | ||||||||
|
zinc finger FYVE-type containing 26 | 0.636 | 0.615 | 4.7E-23 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2001 | 2013 | ||||||||
|
cytochrome P450 family 7 subfamily B member 1 | 0.563 | 0.692 | 3.3E-06 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2008 | 2016 | ||||||||
|
immunoglobulin heavy constant alpha 1 | 0.617 | 0.692 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 1997 | 2019 | |||||||||
|
cytochrome P450 family 2 subfamily U member 1 | 0.722 | 0.462 | 1.4E-03 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2012 | 2019 | ||||||||
|
IgA nephropathy | 0.524 | 0.808 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 1990 | 2019 | |||||||||
|
NIPA magnesium transporter 1 | 0.682 | 0.462 | 5.9E-03 |
|
disease | 0.070 | None | 1.000 | 7 | 1 | 2003 | 2012 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.060 | None | 1.000 | 6 | 1 | 1998 | 2019 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.060 | None | 1.000 | 6 | 1 | 2002 | 2018 | ||||||||
|
heat shock protein family D (Hsp60) member 1 | 0.432 | 0.808 | 0.99 |
|
disease | 0.060 | None | 0.833 | 6 | 0 | 2002 | 2019 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.050 | None | 0.800 | 5 | 1 | 2014 | 2019 | ||||||||
|
calpain 1 | 0.539 | 0.808 | 5.9E-10 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2016 | 2019 | ||||||||
|
DDHD domain containing 1 | 0.716 | 0.423 | 0.90 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2012 | 2018 | ||||||||
|
DDHD domain containing 2 | 0.695 | 0.577 | 1.4E-10 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2012 | 2019 | ||||||||
|
spartin | 0.588 | 0.654 | 3.0E-07 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2002 | 2016 |