| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
serpin family A member 1 | 0.410 | 0.923 | 6.8E-08 |
|
disease | 0.400 | None | 0.909 | 11 | 0 | 1991 | 2018 | ||||||||
|
Cbl proto-oncogene | 0.527 | 0.769 | 6.1E-04 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
molybdenum cofactor sulfurase | 0.617 | 0.654 | 1.6E-19 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
interleukin 18 | 0.365 | 0.923 | 3.1E-02 |
|
disease | 0.210 | None | 1.000 | 2 | 0 | 2006 | 2010 | ||||||||
|
proteinase 3 | 0.503 | 0.808 | 3.8E-05 |
|
disease | 0.200 | None | 0.907 | 54 | 0 | 1994 | 2019 | ||||||||
|
adenosine deaminase 2 | 0.545 | 0.846 | 8.1E-08 |
|
disease | 0.200 | None | 1.000 | 11 | 0 | 2014 | 2020 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.170 | None | 1.000 | 7 | 0 | 2003 | 2018 | ||||||||
|
major histocompatibility complex, class I, B | 0.379 | 0.885 | 3.9E-05 |
|
disease | 0.150 | None | 1.000 | 5 | 0 | 2000 | 2015 | ||||||||
|
MEFV innate immuity regulator, pyrin | 0.440 | 0.885 | 1.0E-14 |
|
disease | 0.140 | None | 1.000 | 4 | 2 | 2007 | 2019 | ||||||||
|
protein tyrosine phosphatase non-receptor type 22 | 0.438 | 0.846 | 3.5E-21 |
|
disease | 0.140 | None | 0.750 | 4 | 1 | 2005 | 2015 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.130 | None | 0.667 | 3 | 2 | 2009 | 2018 | ||||||||
|
membrane spanning 4-domains A1 | 0.411 | 0.846 | 5.1E-05 |
|
disease | 0.130 | None | 1.000 | 3 | 0 | 1997 | 2017 | ||||||||
|
cytotoxic T-lymphocyte associated protein 4 | 0.369 | 0.923 | 0.94 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2018 | 2018 | ||||||||
|
major histocompatibility complex, class II, DP beta 1 | 0.453 | 0.923 | 5.3E-10 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 1993 | 2015 | ||||||||
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2018 | 2020 | ||||||||
|
MYD88 innate immune signal transduction adaptor | 0.414 | 0.923 | 0.12 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
nuclear factor kappa B subunit 1 | 0.396 | 0.923 | 1.00 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
interleukin 12B | 0.480 | 0.885 | 1.1E-04 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2015 | 2015 | ||||||||
|
TNF receptor superfamily member 13C | 0.540 | 0.731 | 0.27 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
Fas cell surface death receptor | 0.372 | 0.923 | 0.81 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
complement factor I | 0.569 | 0.731 | 3.5E-08 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
myeloperoxidase | 0.377 | 0.923 | 7.1E-15 |
|
disease | 0.100 | None | 0.971 | 68 | 1 | 1994 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 1.000 | 19 | 0 | 1990 | 2019 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.100 | None | 0.917 | 12 | 0 | 1991 | 2016 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1996 | 2020 |