| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
transforming growth factor beta receptor 2 | 0.413 | 0.846 | 0.13 |
|
disease | 0.610 | None | 1.000 | 1 | 1 | 2000 | 2000 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.500 | None | 1.000 | 43 | 1 | 1988 | 2019 | ||||||||
|
DCC netrin 1 receptor | 0.471 | 0.808 | 0.99 |
|
disease | 0.500 | None | 0 | 1 | |||||||||||
|
WW domain containing oxidoreductase | 0.453 | 0.808 | 1.2E-15 |
|
disease | 0.410 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
ring finger protein 6 | 0.656 | 0.615 | 1.4E-02 |
|
disease | 0.400 | None | 0 | 0 | |||||||||||
|
cornulin | 0.736 | 0.308 | 1.3E-04 |
|
disease | 0.320 | None | 1.000 | 3 | 1 | 2000 | 2014 | ||||||||
|
leucine zipper tumor suppressor 1 | 0.633 | 0.385 | 0.95 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.200 | None | 0.985 | 134 | 77 | 1990 | 2020 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.200 | None | 1.000 | 31 | 1 | 1993 | 2018 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.200 | None | 0.957 | 23 | 1 | 1994 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.200 | None | 0.952 | 21 | 8 | 2006 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.200 | None | 1.000 | 17 | 4 | 2002 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.170 | None | 1.000 | 8 | 1 | 1992 | 2019 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.160 | None | 1.000 | 6 | 2 | 1996 | 2018 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.150 | None | 0.833 | 6 | 3 | 1994 | 2017 | ||||||||
|
rhomboid 5 homolog 2 | 0.595 | 0.538 | 1.2E-03 |
|
disease | 0.150 | None | 1.000 | 5 | 0 | 1998 | 2012 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
disease | 0.130 | None | 1.000 | 4 | 3 | 1992 | 2016 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
disease | 0.130 | None | 1.000 | 4 | 4 | 1996 | 2016 | ||||||||
|
F-box and WD repeat domain containing 7 | 0.465 | 0.808 | 1.00 |
|
disease | 0.120 | None | 1.000 | 3 | 4 | 2012 | 2018 | ||||||||
|
cancer susceptibility 11 | 0.641 | 0.577 |
|
disease | 0.110 | None | 1.000 | 2 | 3 | 2016 | 2019 | |||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.110 | None | 1.000 | 2 | 3 | 2009 | 2016 | ||||||||
|
signal transducer and activator of transcription 1 | 0.399 | 0.885 | 1.00 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
aldehyde dehydrogenase 2 family member | 0.457 | 0.885 | 3.4E-10 |
|
disease | 0.100 | None | 0.981 | 54 | 2 | 1996 | 2020 | ||||||||
|
single-strand-selective monofunctional uracil-DNA glycosylase 1 | 0.322 | 0.923 | 4.5E-04 |
|
disease | 0.100 | None | 0.969 | 32 | 0 | 2017 | 2020 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
disease | 0.100 | None | 0.964 | 28 | 0 | 1993 | 2019 |