| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
disease | 0.800 | strong | 0.977 | 43 | 12 | 2000 | 2019 | ||||||||
|
zinc finger E-box binding homeobox 2 | 0.471 | 0.808 | 1.00 |
|
disease | 0.400 | strong | 1.000 | 23 | 1 | 2005 | 2019 | ||||||||
|
membrane metalloendopeptidase | 0.407 | 0.808 | 1.5E-18 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2003 | 2003 | ||||||||
|
NLR family CARD domain containing 4 | 0.556 | 0.769 | 9.9E-12 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
phospholipase C gamma 2 | 0.588 | 0.808 | 1.00 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 2004 | 2018 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2004 | 2014 | ||||||||
|
caspase 1 | 0.413 | 0.885 | 3.5E-05 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2007 | 2012 | ||||||||
|
MEFV innate immuity regulator, pyrin | 0.440 | 0.885 | 1.0E-14 |
|
disease | 0.030 | None | 1.000 | 3 | 1 | 2000 | 2017 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2003 | 2012 | ||||||||
|
SLC9A3 regulator 2 | 0.588 | 0.654 | 3.8E-02 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2005 | 2006 | ||||||||
|
SR-related CTD associated factor 11 | 0.584 | 0.731 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2005 | 2006 | ||||||||
|
TNF receptor superfamily member 1A | 0.409 | 0.923 | 0.99 |
|
disease | 0.020 | None | 1.000 | 2 | 1 | 2000 | 2003 | ||||||||
|
atrophin 1 | 0.409 | 0.885 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2003 | 2017 | ||||||||
|
gem nuclear organelle associated protein 2 | 0.597 | 0.654 | 1.5E-06 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2005 | 2006 | ||||||||
|
aminoacyl tRNA synthetase complex interacting multifunctional protein 2 | 0.393 | 0.923 | 8.0E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
interleukin 18 receptor 1 | 0.473 | 0.808 | 8.6E-06 |
|
disease | 0.010 | None | 1.000 | 1 | 1 | 2011 | 2011 | ||||||||
|
mitogen-activated protein kinase 14 | 0.379 | 0.923 | 0.37 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
NLR family pyrin domain containing 12 | 0.569 | 0.846 | 3.6E-28 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
GRB2 related adaptor protein 2 | 0.394 | 0.923 | 1.5E-04 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
Bruton tyrosine kinase | 0.464 | 0.808 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
nucleotide binding oligomerization domain containing 2 | 0.423 | 0.923 | 2.0E-30 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
ret proto-oncogene | 0.392 | 0.885 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.397 | 0.923 | 2.5E-02 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
DNA polymerase delta interacting protein 2 | 0.396 | 0.923 | 0.41 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 |