Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
Squamous cell carcinoma of the head and neck
disease 0.800 strong 0.952 21 3 1972 2019
Entrez Id: 3621
Gene Symbol: ING1
ING1
inhibitor of growth family member 1 0.573 0.692 9.7E-03
Squamous cell carcinoma of the head and neck
disease 0.710 None 1.000 2 3 2000 2000
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
Squamous cell carcinoma of the head and neck
disease 0.500 None 0.982 277 18 1992 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
Squamous cell carcinoma of the head and neck
disease 0.500 None 0.973 219 86 1991 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
Squamous cell carcinoma of the head and neck
disease 0.500 None 0.983 115 9 1994 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
Squamous cell carcinoma of the head and neck
disease 0.500 None 1.000 68 29 2001 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
Squamous cell carcinoma of the head and neck
disease 0.440 None 1.000 5 5 2013 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
Squamous cell carcinoma of the head and neck
disease 0.400 None 1.000 52 1 1994 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
Squamous cell carcinoma of the head and neck
disease 0.400 None 0.957 47 0 2000 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
Squamous cell carcinoma of the head and neck
disease 0.400 None 1.000 32 0 2005 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
Squamous cell carcinoma of the head and neck
disease 0.400 None 0.966 29 3 1999 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
notch receptor 1 0.369 0.885 1.00
Squamous cell carcinoma of the head and neck
disease 0.400 None 1.000 20 1 2011 2019
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
Squamous cell carcinoma of the head and neck
disease 0.400 None 0.933 15 1 2000 2020
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
cyclin dependent kinase 4 0.412 0.808 6.3E-02
Squamous cell carcinoma of the head and neck
disease 0.390 None 1.000 10 0 1995 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
O-6-methylguanine-DNA methyltransferase 0.412 0.885 1.2E-07
Squamous cell carcinoma of the head and neck
disease 0.390 None 0.800 10 2 2004 2019
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
Yes associated protein 1 0.432 0.808 1.00
Squamous cell carcinoma of the head and neck
disease 0.380 None 1.000 9 0 2010 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
Squamous cell carcinoma of the head and neck
disease 0.370 None 1.000 8 0 2006 2018
Entrez Id: 841
Gene Symbol: CASP8
CASP8
caspase 8 0.404 0.923 3.7E-06
Squamous cell carcinoma of the head and neck
disease 0.360 None 1.000 7 0 2009 2016
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
Squamous cell carcinoma of the head and neck
disease 0.360 None 1.000 6 0 1996 2019
Entrez Id: 7465
Gene Symbol: WEE1
WEE1
WEE1 G2 checkpoint kinase 0.545 0.769 1.00
Squamous cell carcinoma of the head and neck
disease 0.360 None 1.000 6 0 2014 2019
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
cyclin dependent kinase 2 0.456 0.692 0.61
Squamous cell carcinoma of the head and neck
disease 0.340 None 0.800 5 0 1994 2018
Entrez Id: 8900
Gene Symbol: CCNA1
CCNA1
cyclin A1 0.588 0.654 4.3E-04
Squamous cell carcinoma of the head and neck
disease 0.330 None 1.000 5 0 2004 2018
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
ATP binding cassette subfamily C member 1 0.445 0.808 1.2E-03
Squamous cell carcinoma of the head and neck
disease 0.330 None 1.000 4 0 2000 2017
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
Squamous cell carcinoma of the head and neck
disease 0.330 None 1.000 4 1 2007 2017
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
cyclin dependent kinase 6 0.471 0.731 0.98
Squamous cell carcinoma of the head and neck
disease 0.320 None 1.000 3 0 2016 2018