| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
group | 0.100 | None | 1.000 | 26 | 0 | 2006 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
group | 0.100 | None | 1.000 | 16 | 0 | 1990 | 2020 | ||||||||
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
group | 0.100 | None | 1.000 | 14 | 1 | 2000 | 2019 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
group | 0.100 | None | 1.000 | 13 | 0 | 2000 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
group | 0.100 | None | 0.917 | 12 | 0 | 2000 | 2020 | ||||||||
|
major histocompatibility complex, class I, B | 0.379 | 0.885 | 3.9E-05 |
|
group | 0.100 | None | 0.909 | 11 | 0 | 1995 | 2020 | ||||||||
|
nucleotide binding oligomerization domain containing 2 | 0.423 | 0.923 | 2.0E-30 |
|
group | 0.100 | None | 1.000 | 11 | 0 | 2002 | 2017 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
group | 0.100 | None | 1.000 | 10 | 0 | 1998 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
group | 0.100 | None | 0.900 | 10 | 0 | 2002 | 2019 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
group | 0.090 | None | 1.000 | 9 | 0 | 2010 | 2019 | ||||||||
|
MEFV innate immuity regulator, pyrin | 0.440 | 0.885 | 1.0E-14 |
|
group | 0.070 | None | 1.000 | 7 | 1 | 2003 | 2018 | ||||||||
|
protein tyrosine phosphatase non-receptor type 6 | 0.485 | 0.769 | 1.00 |
|
group | 0.060 | None | 1.000 | 6 | 0 | 2011 | 2020 | ||||||||
|
nuclear receptor subfamily 3 group C member 1 | 0.393 | 0.885 | 0.97 |
|
group | 0.060 | None | 1.000 | 6 | 0 | 2005 | 2019 | ||||||||
|
interleukin 1 receptor antagonist | 0.373 | 0.923 | 3.1E-02 |
|
group | 0.060 | None | 0.833 | 6 | 0 | 1995 | 2017 | ||||||||
|
activating transcription factor 7 interacting protein | 0.543 | 0.769 | 1.00 |
|
group | 0.050 | None | 1.000 | 5 | 0 | 2000 | 2018 | ||||||||
|
Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 |
|
group | 0.050 | None | 1.000 | 5 | 0 | 2011 | 2018 | |||||||||
|
nuclear receptor subfamily 0 group B member 2 | 0.474 | 0.808 | 8.3E-06 |
|
group | 0.050 | None | 1.000 | 5 | 0 | 2011 | 2018 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
group | 0.050 | None | 1.000 | 5 | 0 | 1999 | 2019 | ||||||||
|
beta-2-microglobulin | 0.447 | 0.846 | 0.56 |
|
group | 0.050 | None | 1.000 | 5 | 0 | 1990 | 1998 | ||||||||
|
mitogen-activated protein kinase kinase kinase 7 | 0.477 | 0.808 | 1.00 |
|
group | 0.040 | None | 1.000 | 4 | 0 | 2017 | 2020 | ||||||||
|
forkhead box P3 | 0.368 | 0.846 | 0.99 |
|
group | 0.040 | None | 1.000 | 4 | 0 | 2012 | 2018 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
group | 0.040 | None | 1.000 | 4 | 0 | 2011 | 2019 | ||||||||
|
interleukin 18 | 0.365 | 0.923 | 3.1E-02 |
|
group | 0.040 | None | 1.000 | 4 | 0 | 2007 | 2019 | ||||||||
|
aquaporin 4 | 0.456 | 0.885 | 2.3E-03 |
|
group | 0.040 | None | 1.000 | 4 | 0 | 2009 | 2017 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
group | 0.040 | None | 1.000 | 4 | 0 | 2004 | 2012 |