| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.200 | None | 1.000 | 59 | 6 | 1994 | 2020 | ||||||||
|
gremlin 1, DAN family BMP antagonist | 0.508 | 0.808 | 0.47 |
|
disease | 0.130 | None | 1.000 | 4 | 2 | 1999 | 2019 | ||||||||
|
bone morphogenetic protein 4 | 0.422 | 0.808 | 0.96 |
|
disease | 0.110 | None | 1.000 | 2 | 1 | 2015 | 2019 | ||||||||
|
cadherin 3 | 0.560 | 0.615 | 2.8E-10 |
|
disease | 0.110 | None | 1.000 | 2 | 1 | 2008 | 2019 | ||||||||
|
solute carrier organic anion transporter family member 2A1 | 0.578 | 0.654 | 2.3E-13 |
|
disease | 0.110 | None | 1.000 | 2 | 1 | 2012 | 2019 | ||||||||
|
cancer susceptibility 8 | 0.670 | 0.462 |
|
disease | 0.110 | None | 1.000 | 2 | 4 | 2019 | 2019 | |||||||||
|
mutY DNA glycosylase | 0.521 | 0.769 | 1.3E-18 |
|
disease | 0.100 | None | 0.978 | 46 | 2 | 2002 | 2018 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 0.973 | 37 | 3 | 1992 | 2017 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.100 | None | 0.967 | 30 | 2 | 1994 | 2018 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.100 | None | 0.895 | 19 | 2 | 1998 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.100 | None | 1.000 | 19 | 0 | 1991 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 18 | 0 | 1997 | 2015 | ||||||||
|
cytochrome c oxidase subunit II | 0.352 | 0.962 |
|
disease | 0.100 | None | 1.000 | 13 | 0 | 1994 | 2017 | |||||||||
|
MT-CO2 pseudogene 12 | 0.368 | 0.962 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1994 | 2017 | |||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 2001 | 2018 | ||||||||
|
glutathione S-transferase mu 1 | 0.380 | 0.923 | 2.1E-03 |
|
disease | 0.100 | None | 0.600 | 10 | 1 | 1995 | 2012 | ||||||||
|
solute carrier family 25 member 26 | 0.716 | 0.308 | 2.6E-07 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2019 | 2019 | ||||||||
|
FKBP prolyl isomerase 5 | 0.524 | 0.769 | 0.73 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2019 | 2019 | ||||||||
|
LDL receptor related protein 1 | 0.482 | 0.769 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2019 | 2019 | ||||||||
|
SMAD family member 9 | 0.666 | 0.308 | 6.4E-05 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2019 | 2019 | ||||||||
|
SMAD family member 3 | 0.415 | 0.923 | 0.80 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2019 | 2019 | ||||||||
|
Kruppel like factor 5 | 0.534 | 0.769 | 0.82 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2019 | 2019 | ||||||||
|
SMAD family member 6 | 0.579 | 0.731 | 3.6E-20 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2019 | 2019 | ||||||||
|
SMAD family member 7 | 0.470 | 0.769 | 0.55 |
|
disease | 0.100 | None | 1.000 | 1 | 2 | 2019 | 2019 | ||||||||
|
transcription factor 7 like 2 | 0.485 | 0.846 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2019 | 2019 |