| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.400 | None | 0.970 | 134 | 3 | 1994 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.100 | None | 0.918 | 49 | 0 | 1995 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 1.000 | 28 | 5 | 1994 | 2017 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.100 | None | 0.947 | 19 | 2 | 1997 | 2019 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 1996 | 2014 | ||||||||
|
estrogen receptor 2 | 0.400 | 0.923 | 4.5E-08 |
|
disease | 0.080 | None | 1.000 | 8 | 2 | 2005 | 2017 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2003 | 2016 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.050 | None | 0.800 | 5 | 0 | 1999 | 2016 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2007 | 2018 | ||||||||
|
fragile histidine triad diadenosine triphosphatase | 0.444 | 0.846 | 5.7E-03 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 1996 | 2010 | ||||||||
|
EMSY transcriptional repressor, BRCA2 interacting | 0.628 | 0.423 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2004 | 2016 | ||||||||
|
glutathione S-transferase mu 1 | 0.380 | 0.923 | 2.1E-03 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2000 | 2010 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 1 | 2009 | 2014 | ||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
disease | 0.040 | None | 1.000 | 4 | 3 | 1999 | 2017 | ||||||||
|
FA complementation group D2 | 0.479 | 0.885 | 1.1E-30 |
|
disease | 0.040 | None | 1.000 | 4 | 1 | 2006 | 2019 | ||||||||
|
RAD51 recombinase | 0.447 | 0.846 | 2.7E-02 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2007 | 2017 | ||||||||
|
serine/threonine kinase 11 | 0.435 | 0.808 | 0.99 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 1998 | 2006 | ||||||||
|
poly(ADP-ribose) polymerase 1 | 0.389 | 0.923 | 3.3E-04 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2012 | 2016 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2008 | 2014 | ||||||||
|
X-ray repair cross complementing 1 | 0.421 | 0.923 | 6.3E-09 |
|
disease | 0.040 | None | 1.000 | 4 | 2 | 2007 | 2015 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1999 | 2005 | ||||||||
|
insulin like growth factor 1 | 0.318 | 0.885 | 0.27 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2007 | 2014 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.030 | None | 1.000 | 3 | 2 | 2004 | 2017 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 2012 | 2017 | ||||||||
|
H2A.X variant histone | 0.484 | 0.808 | 0.18 |
|
disease | 0.030 | None | 1.000 | 3 | 2 | 2008 | 2011 |