Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. 21690266

2011
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD Maternal low-protein diet or hypercholesterolemia reduces circulating essential amino acids and leads to intrauterine growth restriction. 19073773

2009
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD Ultrastructural changes in a murine model of graded Bruch membrane lipoidal degeneration and corresponding VEGF164 detection. 18172117

2008
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD LDL receptor deficiency results in decreased cell proliferation and presynaptic bouton density in the murine hippocampus. 17720268

2007
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD Attenuated corticosterone response to chronic ACTH stimulation in hepatic lipase-deficient mice: evidence for a role for hepatic lipase in adrenal physiology. 16368783

2006
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet. 16835442

2006
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD Disruption of autosomal recessive hypercholesterolemia gene shows different phenotype in vitro and in vivo. 15472122

2004
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus. 15207278

2004
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice. 12847522

2003
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker MGD Transbilayer distribution of cholesterol is modified in brain synaptic plasma membranes of knockout mice deficient in the low-density lipoprotein receptor, apolipoprotein E, or both proteins. 9326295

1997