Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Abnormal astrocyte differentiation and defective cellular interactions in wobbler mouse spinal cord. 8006678

1994
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Transforming growth factor alpha (TGF alpha) expression in degenerating motoneurons of the murine mutant wobbler: a neuronal signal for astrogliosis? 8027772

1994
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Retardation of fast axonal transport in wobbler mice. 8390608

1993
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Thyrotropin-releasing hormone (TRH) neurons sprout in cervical spinal cord of Wobbler mouse. 8281455

1993
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Alteration in the levels of thyrotropin releasing hormone, substance P and enkephalins in the spinal cord, brainstem, hypothalamus and midbrain of the Wobbler mouse at different stages of the motoneuron disease. 1383870

1992
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Defect of sperm assembly in a neurological mutant of the mouse, wobbler (WR). 1955109

1991
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Astrocyte overgrowth in the brain stem and spinal cord of mice affected by spinal atrophy, wobbler. 3142758

1988
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Impaired slow axonal transport in wobbler mouse motor neuron disease. 3947038

1986
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Substance P neurons sprout in the cervical spinal cord of the wobbler mouse: a model for motoneuron disease. 2432278

1986
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Animal model of human disease: Werdnig-Hoffmann disease (infantile spinal muscular atrophy). 7416238

1980
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Reduced protein synthesis in spinal anterior horn neurons in wobbler mouse mutant. 7349996

1980
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Decreased spinal cord cGMP in murine (wobbler) spontaneous lower motor neuron degeneration. 210748

1978
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD The fine structure of the cervical spinal cord, ventral root and brachial nerves in the wobbler (wr) mouse. 1117319

1975
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD Abnormalities of peripheral nerves in murine muscular dystrophy. 4120487

1973
Entrez Id: 51542
Gene Symbol: VPS54
VPS54
CUI: C0043116
Disease: HMN (Hereditary Motor Neuropathy) Proximal Type I
HMN (Hereditary Motor Neuropathy) Proximal Type I 		0.200 Biomarker MGD An hereditary motor neurone disease with progressive denervation of muscle in the mouse: the mutant 'wobbler'. 5709840

1968