Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7466
Gene Symbol: WFS1
WFS1
CUI: C0043207
Disease: Wolfram Syndrome
Wolfram Syndrome 		0.900 Biomarker MGD There is no data about the energy metabolism of patients with Wolfram syndrome caused by mutations in the wolframin (Wfs1) gene. 24710642

2014
Entrez Id: 7466
Gene Symbol: WFS1
WFS1
CUI: C0043207
Disease: Wolfram Syndrome
Wolfram Syndrome 		0.900 Biomarker MGD Wolfram syndrome, caused by mutations in the wolframin (Wfs1) gene, is characterised by juvenile-onset diabetes mellitus, progressive optic atrophy, diabetes insipidus and deafness.Diabetes tend to start earlier in boys. 21031341

2011
Entrez Id: 7466
Gene Symbol: WFS1
WFS1
CUI: C0043207
Disease: Wolfram Syndrome
Wolfram Syndrome 		0.900 Biomarker MGD Wfs1 gene deletion causes growth retardation in mice and interferes with the growth hormone pathway. 19293327

2009
Entrez Id: 7466
Gene Symbol: WFS1
WFS1
CUI: C0043207
Disease: Wolfram Syndrome
Wolfram Syndrome 		0.900 Biomarker MGD Behavioral and gene expression analyses of Wfs1 knockout mice as a possible animal model of mood disorder. 18343518

2008
Entrez Id: 7466
Gene Symbol: WFS1
WFS1
CUI: C0043207
Disease: Wolfram Syndrome
Wolfram Syndrome 		0.900 Biomarker MGD These WFS1 mutant mice provide a valuable tool for understanding better the pathophysiology of Wolfram syndrome as well as WFS1 function. 15056606

2004