| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
histamine receptor H3 | 0.647 | 0.462 | 4.1E-02 |
|
disease | 0.510 | None | 1.000 | 1 | 0 | 1999 | 2019 | ||||||||
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.400 | None | 1.000 | 20 | 0 | 1997 | 2020 | ||||||||
|
nerve growth factor | 0.391 | 0.885 | 0.82 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 1995 | 2009 | ||||||||
|
sigma non-opioid intracellular receptor 1 | 0.544 | 0.808 | 0.17 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2000 | 2002 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 1997 | 2011 | ||||||||
|
colony stimulating factor 2 | 0.330 | 0.962 | 0.83 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 1996 | 2019 | ||||||||
|
butyrylcholinesterase | 0.447 | 0.923 | 1.1E-13 |
|
disease | 0.220 | None | 1.000 | 2 | 0 | 2011 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.100 | None | 0.917 | 12 | 2 | 2005 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.100 | None | 1.000 | 11 | 1 | 1999 | 2016 | ||||||||
|
acetylcholinesterase (Cartwright blood group) | 0.445 | 0.885 | 1.00 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2017 | 2019 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.070 | None | 1.000 | 7 | 1 | 2007 | 2019 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2008 | 2016 | ||||||||
|
TAR DNA binding protein | 0.493 | 0.808 | 0.99 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2015 | 2020 | ||||||||
|
RB binding protein 4, chromatin remodeling factor | 0.644 | 0.654 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2013 | 2019 | ||||||||
|
parvalbumin | 0.547 | 0.692 | 8.7E-02 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2018 | 2020 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2017 | 2019 | ||||||||
|
cAMP responsive element binding protein 1 | 0.463 | 0.885 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2006 | 2018 | ||||||||
|
leucine rich glioma inactivated 1 | 0.568 | 0.731 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2017 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2009 | 2014 | ||||||||
|
GA binding protein transcription factor subunit alpha | 0.379 | 0.885 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2019 | 2019 | ||||||||
|
FUS RNA binding protein | 0.470 | 0.846 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2012 | 2017 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.020 | None | 1.000 | 2 | 1 | 2016 | 2019 | ||||||||
|
adrenomedullin | 0.436 | 0.808 | 4.1E-02 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2017 | 2019 | ||||||||
|
glycogen synthase kinase 3 beta | 0.430 | 0.846 | 0.96 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2017 | 2019 | ||||||||
|
cannabinoid receptor 1 | 0.446 | 0.808 | 0.51 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2018 | 2018 |