Source: BEFREE
| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.400 | None | 0.994 | 159 | 2 | 2003 | 2019 | ||||||||
|
ret proto-oncogene | 0.392 | 0.885 | 1.00 |
|
disease | 0.400 | None | 1.000 | 83 | 5 | 1996 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.370 | None | 1.000 | 7 | 0 | 2012 | 2016 | ||||||||
|
protein kinase cAMP-dependent type I regulatory subunit alpha | 0.401 | 0.846 | 1.00 |
|
disease | 0.350 | None | 1.000 | 5 | 0 | 2002 | 2019 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
disease | 0.330 | None | 1.000 | 3 | 3 | 2015 | 2017 | ||||||||
|
solute carrier family 5 member 5 | 0.499 | 0.769 | 2.9E-03 |
|
disease | 0.100 | None | 1.000 | 65 | 0 | 1997 | 2020 | ||||||||
|
thyroglobulin | 0.480 | 0.808 | 2.9E-59 |
|
disease | 0.100 | None | 0.917 | 48 | 1 | 1985 | 2019 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.100 | None | 0.972 | 36 | 0 | 1997 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 35 | 1 | 2005 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 0.906 | 32 | 3 | 1993 | 2018 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 32 | 0 | 2005 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 32 | 1 | 2005 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.100 | None | 1.000 | 32 | 0 | 2005 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.100 | None | 1.000 | 28 | 0 | 2004 | 2019 | ||||||||
|
thyroid stimulating hormone receptor | 0.486 | 0.808 | 3.0E-15 |
|
disease | 0.100 | None | 0.929 | 28 | 0 | 1992 | 2018 | ||||||||
|
patched 1 | 0.398 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.962 | 26 | 2 | 1998 | 2018 | ||||||||
|
telomerase reverse transcriptase | 0.374 | 0.846 | 0.99 |
|
disease | 0.100 | None | 0.958 | 24 | 2 | 2004 | 2020 | ||||||||
|
coiled-coil domain containing 6 | 0.517 | 0.808 | 0.58 |
|
disease | 0.100 | None | 1.000 | 23 | 1 | 1996 | 2016 | ||||||||
|
TERT 5' regulatory region | 0.464 | 0.731 |
|
disease | 0.100 | None | 1.000 | 22 | 0 | 2013 | 2020 | |||||||||
|
coagulation factor IX | 0.465 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 20 | 0 | 1998 | 2016 | ||||||||
|
taste 2 receptor member 38 | 0.531 | 0.808 | 0.13 |
|
disease | 0.100 | None | 1.000 | 20 | 0 | 1998 | 2016 | ||||||||
|
paired box 8 | 0.477 | 0.731 | 1.00 |
|
disease | 0.100 | None | 1.000 | 18 | 0 | 2000 | 2019 | ||||||||
|
forkhead box E1 | 0.573 | 0.731 | 0.79 |
|
disease | 0.100 | None | 1.000 | 16 | 3 | 2001 | 2020 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 1.000 | 16 | 1 | 1997 | 2019 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.100 | None | 1.000 | 16 | 0 | 2001 | 2017 |