Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4653
Gene Symbol: MYOC
MYOC 		myocilin 0.595 0.500 7.6E-12
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.700 None 0.987 55 6 1996 2019
Entrez Id: 10133
Gene Symbol: OPTN
OPTN 		optineurin 0.548 0.808 5.9E-18
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.500 None 0.950 9 1 2002 2014
Entrez Id: 134430
Gene Symbol: WDR36
WDR36 		WD repeat domain 36 0.751 0.192 5.7E-04
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.440 None 1.000 1 1 2005 2011
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1 		CDKN2B antisense RNA 1 0.491 0.769
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.430 None 1.000 3 3 2011 2018
Entrez Id: 54499
Gene Symbol: TMCO1
TMCO1 		transmembrane and coiled-coil domains 1 0.588 0.654 9.4E-10
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.410 None 1.000 1 0 2011 2018
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1 		cytochrome P450 family 1 subfamily B member 1 0.457 0.769 2.2E-05
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.200 None 1.000 9 4 2002 2018
Entrez Id: 4016
Gene Symbol: LOXL1
LOXL1 		lysyl oxidase like 1 0.590 0.615 0.89
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.160 None 0.857 4 3 2008 2014
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B 		LIM homeobox transcription factor 1 beta 0.565 0.731 0.75
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.130 None 1.000 3 0 1998 2018
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B 		cyclin dependent kinase inhibitor 2B 0.417 0.769 7.3E-03
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.120 None 1.000 2 1 2011 2012
Entrez Id: 136371
Gene Symbol: ASB10
ASB10 		ankyrin repeat and SOCS box containing 10 0.805 0.077 2.6E-12
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.120 None 1.000 2 0 2012 2012
Entrez Id: 4990
Gene Symbol: SIX6
SIX6 		SIX homeobox 6 0.588 0.654 0.52
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.110 None 1.000 1 0 2015 2016
Entrez Id: 348
Gene Symbol: APOE
APOE 		apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.070 None 1.000 2 0 2002 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.060 None 0.833 4 2 2002 2015
Entrez Id: 5362
Gene Symbol: PLXNA2
PLXNA2 		plexin A2 0.447 0.808 1.1E-06
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.050 None 1.000 5 0 2017 2018
Entrez Id: 8378
Gene Symbol: LOH19CR1
LOH19CR1 		loss of heterozygosity, 19, chromosomal region 1 0.569 0.808
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.040 None 1.000 4 0 2002 2019
Entrez Id: 6223
Gene Symbol: RPS19
RPS19 		ribosomal protein S19 0.480 0.846 0.92
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.040 None 1.000 4 0 2002 2019
Entrez Id: 4976
Gene Symbol: OPA1
OPA1 		OPA1 mitochondrial dynamin like GTPase 0.510 0.846 0.99
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.040 None 1.000 2 0 2002 2019
Entrez Id: 6495
Gene Symbol: SIX1
SIX1 		SIX homeobox 1 0.496 0.692 0.65
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.030 None 1.000 3 0 2011 2015
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.030 None 1.000 3 2 2004 2010
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2 		solute carrier family 6 member 2 0.490 0.846 8.2E-02
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.020 None 1.000 2 0 2018 2018
Entrez Id: 578
Gene Symbol: BAK1
BAK1 		BCL2 antagonist/killer 1 0.555 0.769 7.4E-06
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.020 None 1.000 2 0 2019 2019
Entrez Id: 28
Gene Symbol: ABO
ABO 		ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase 0.427 0.885
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.020 None 1.000 2 0 1978 1996
Entrez Id: 7124
Gene Symbol: TNF
TNF 		tumor necrosis factor 0.231 0.962 0.80
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.020 None 1.000 2 0 2009 2013
Entrez Id: 93145
Gene Symbol: OLFM2
OLFM2 		olfactomedin 2 0.780 0.231 8.0E-02
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.020 None 1.000 2 1 2006 2017
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		adrenoceptor beta 2 0.442 0.923 0.53
CUI: C0017612
Disease: Glaucoma, Open-Angle
Glaucoma, Open-Angle 		disease 0.020 None 1.000 2 0 2006 2018