| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
neurofibromin 1 | 0.440 | 0.885 | 0.90 |
|
disease | 1.000 | None | 0.976 | 423 | 15 | 1977 | 2020 | ||||||||
|
sprouty related EVH1 domain containing 1 | 0.644 | 0.577 | 0.97 |
|
disease | 0.400 | None | 0.864 | 22 | 0 | 2007 | 2020 | ||||||||
|
neurofibromin 2 | 0.468 | 0.885 | 1.00 |
|
disease | 0.300 | None | 1.000 | 14 | 0 | 1996 | 2020 | ||||||||
|
RAS p21 protein activator 1 | 0.481 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.974 | 38 | 2 | 1990 | 2018 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 0.929 | 28 | 0 | 1990 | 2018 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.100 | None | 0.938 | 16 | 2 | 2009 | 2019 | ||||||||
|
KIT proto-oncogene, receptor tyrosine kinase | 0.366 | 0.808 | 0.98 |
|
disease | 0.100 | None | 1.000 | 15 | 0 | 2004 | 2014 | ||||||||
|
protein tyrosine phosphatase non-receptor type 11 | 0.385 | 0.923 | 1.00 |
|
disease | 0.100 | None | 0.933 | 15 | 2 | 1996 | 2015 | ||||||||
|
regulator of G protein signaling 6 | 0.564 | 0.769 | 0.44 |
|
disease | 0.100 | None | 1.000 | 14 | 0 | 1992 | 2018 | ||||||||
|
ret proto-oncogene | 0.392 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.929 | 14 | 0 | 2002 | 2015 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.100 | None | 1.000 | 13 | 0 | 1999 | 2019 | ||||||||
|
platelet derived growth factor receptor alpha | 0.415 | 0.808 | 1.00 |
|
disease | 0.100 | None | 1.000 | 13 | 0 | 2005 | 2017 | ||||||||
|
succinate dehydrogenase complex subunit D | 0.472 | 0.885 | 0.34 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2005 | 2017 | ||||||||
|
mannose receptor C-type 1 | 0.413 | 0.846 | 0.94 |
|
disease | 0.090 | None | 1.000 | 9 | 1 | 2004 | 2016 | ||||||||
|
von Hippel-Lindau tumor suppressor | 0.443 | 0.846 | 8.0E-02 |
|
disease | 0.080 | None | 0.875 | 8 | 0 | 1995 | 2017 | ||||||||
|
succinate dehydrogenase complex iron sulfur subunit B | 0.474 | 0.846 | 2.4E-04 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2003 | 2017 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 1992 | 2019 | ||||||||
|
mitogen-activated protein kinase kinase 7 | 0.419 | 0.808 | 1.00 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2013 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.080 | None | 0.875 | 8 | 0 | 2000 | 2018 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2006 | 2018 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2005 | 2019 | ||||||||
|
SUZ12 polycomb repressive complex 2 subunit | 0.529 | 0.577 | 1.00 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2004 | 2017 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2009 | 2016 | ||||||||
|
growth hormone 1 | 0.373 | 0.923 | 3.0E-02 |
|
disease | 0.060 | None | 0.667 | 6 | 0 | 1987 | 2019 | ||||||||
|
single-strand-selective monofunctional uracil-DNA glycosylase 1 | 0.322 | 0.923 | 4.5E-04 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2017 | 2019 |