Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
cyclin dependent kinase 6 0.471 0.731 0.98
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.310 None 1.000 1 0 2017 2017
Entrez Id: 6794
Gene Symbol: STK11
STK11
serine/threonine kinase 11 0.435 0.808 0.99
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.310 None 1.000 1 0 2012 2012
Entrez Id: 4293
Gene Symbol: MAP3K9
MAP3K9
mitogen-activated protein kinase kinase kinase 9 0.711 0.269 0.12
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.310 None 1.000 1 0 2011 2011
Entrez Id: 2043
Gene Symbol: EPHA4
EPHA4
EPH receptor A4 0.566 0.846 1.00
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.310 None 1.000 1 0 1997 1997
Entrez Id: 5587
Gene Symbol: PRKD1
PRKD1
protein kinase D1 0.531 0.846 6.6E-07
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.310 None 1.000 1 0 2017 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 0.992 400 8 2003 2020
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
mitogen-activated protein kinase kinase 7 0.419 0.808 1.00
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 0.986 71 1 2011 2020
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
cytotoxic T-lymphocyte associated protein 4 0.369 0.923 0.94
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 0.983 59 0 2005 2020
Entrez Id: 3558
Gene Symbol: IL2
IL2
interleukin 2 0.336 0.885 0.48
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 0.978 46 0 1990 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 0.972 36 0 2012 2019
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1
programmed cell death 1 0.402 0.846 0.42
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 31 0 2015 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 23 5 2007 2019
Entrez Id: 2315
Gene Symbol: MLANA
MLANA
melan-A 0.579 0.692 1.3E-09
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 20 0 1998 2019
Entrez Id: 7299
Gene Symbol: TYR
TYR
tyrosinase 0.473 0.808 5.0E-32
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 19 0 1994 2018
Entrez Id: 3815
Gene Symbol: KIT
KIT
KIT proto-oncogene, receptor tyrosine kinase 0.366 0.808 0.98
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 18 1 2006 2019
Entrez Id: 388015
Gene Symbol: RTL1
RTL1
retrotransposon Gag like 1 0.554 0.808 5.6E-03
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 14 0 1994 2018
Entrez Id: 22882
Gene Symbol: ZHX2
ZHX2
zinc fingers and homeoboxes 2 0.510 0.654 3.4E-02
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 11 0 2011 2017
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
Raf-1 proto-oncogene, serine/threonine kinase 0.418 0.885 0.85
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 11 1 2011 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 10 1 2001 2019
Entrez Id: 6490
Gene Symbol: PMEL
PMEL
premelanosome protein 0.531 0.769 3.1E-18
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.100 None 1.000 10 0 1998 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.090 None 0.889 9 0 2018 2019
Entrez Id: 6285
Gene Symbol: S100B
S100B
S100 calcium binding protein B 0.383 0.923 4.4E-02
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.080 None 1.000 8 0 2005 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.080 None 1.000 8 0 2008 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.080 None 0.875 8 0 2002 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma
disease 0.080 None 1.000 8 0 2008 2019