Source: BEFREE
| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
egl-9 family hypoxia inducible factor 1 | 0.540 | 0.731 | 0.97 |
|
disease | 0.350 | strong | 0.833 | 5 | 0 | 2007 | 2015 | ||||||||
|
ret proto-oncogene | 0.392 | 0.885 | 1.00 |
|
disease | 0.200 | None | 0.963 | 163 | 24 | 1990 | 2019 | ||||||||
|
succinate dehydrogenase complex iron sulfur subunit B | 0.474 | 0.846 | 2.4E-04 |
|
disease | 0.200 | None | 0.974 | 117 | 0 | 2001 | 2020 | ||||||||
|
succinate dehydrogenase complex subunit D | 0.472 | 0.885 | 0.34 |
|
disease | 0.200 | None | 0.990 | 101 | 3 | 2000 | 2020 | ||||||||
|
von Hippel-Lindau tumor suppressor | 0.443 | 0.846 | 8.0E-02 |
|
disease | 0.200 | None | 0.988 | 85 | 10 | 1995 | 2020 | ||||||||
|
succinate dehydrogenase complex subunit C | 0.517 | 0.846 | 2.0E-04 |
|
disease | 0.200 | None | 1.000 | 25 | 1 | 2003 | 2019 | ||||||||
|
transmembrane protein 127 | 0.638 | 0.615 | 1.3E-02 |
|
disease | 0.200 | None | 1.000 | 19 | 0 | 2010 | 2020 | ||||||||
|
MYC associated factor X | 0.553 | 0.769 | 0.83 |
|
disease | 0.200 | None | 1.000 | 16 | 0 | 2011 | 2019 | ||||||||
|
succinate dehydrogenase complex flavoprotein subunit A | 0.517 | 0.731 | 2.6E-10 |
|
disease | 0.200 | None | 1.000 | 13 | 1 | 2005 | 2018 | ||||||||
|
succinate dehydrogenase complex assembly factor 2 | 0.604 | 0.692 | 2.8E-06 |
|
disease | 0.200 | None | 1.000 | 11 | 0 | 2010 | 2017 | ||||||||
|
fumarate hydratase | 0.489 | 0.846 | 8.8E-02 |
|
disease | 0.160 | None | 1.000 | 6 | 0 | 2003 | 2019 | ||||||||
|
malate dehydrogenase 2 | 0.595 | 0.731 | 6.7E-03 |
|
disease | 0.150 | None | 1.000 | 5 | 0 | 2015 | 2018 | ||||||||
|
kinesin family member 1B | 0.516 | 0.808 | 1.00 |
|
disease | 0.130 | None | 1.000 | 3 | 0 | 2008 | 2014 | ||||||||
|
dihydrolipoamide S-succinyltransferase | 0.653 | 0.615 | 0.48 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
sorbitol dehydrogenase | 0.552 | 0.769 | 4.5E-08 |
|
disease | 0.100 | None | 1.000 | 34 | 0 | 2003 | 2020 | ||||||||
|
sarcosine dehydrogenase | 0.523 | 0.846 | 5.3E-16 |
|
disease | 0.100 | None | 1.000 | 34 | 0 | 2003 | 2020 | ||||||||
|
serine dehydratase | 0.534 | 0.769 | 1.4E-04 |
|
disease | 0.100 | None | 1.000 | 34 | 0 | 2003 | 2020 | ||||||||
|
adrenomedullin | 0.436 | 0.808 | 4.1E-02 |
|
disease | 0.100 | None | 1.000 | 32 | 0 | 1993 | 2019 | ||||||||
|
nerve growth factor | 0.391 | 0.885 | 0.82 |
|
disease | 0.100 | None | 0.962 | 26 | 0 | 1985 | 2019 | ||||||||
|
somatostatin | 0.399 | 0.885 | 0.34 |
|
disease | 0.100 | None | 0.933 | 15 | 0 | 1995 | 2019 | ||||||||
|
proopiomelanocortin | 0.356 | 0.846 | 1.2E-04 |
|
disease | 0.100 | None | 0.929 | 14 | 0 | 1982 | 2019 | ||||||||
|
endothelial PAS domain protein 1 | 0.454 | 0.731 | 0.60 |
|
disease | 0.100 | None | 1.000 | 14 | 0 | 2001 | 2019 | ||||||||
|
chromogranin A | 0.490 | 0.808 | 3.0E-02 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 1986 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 0.750 | 12 | 0 | 1991 | 2020 | ||||||||
|
tyrosine hydroxylase | 0.462 | 0.885 | 1.7E-06 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 1985 | 2016 |