Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
Compound heterozygosity for two MSH6 mutations in a patient with early onset colorectal cancer, vitiligo and systemic lupus erythematosus.
|
18409202 |
2008 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
RNA-based mutation analysis identifies an unusual MSH6 splicing defect and circumvents PMS2 pseudogene interference.
|
18030674 |
2008 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
Zebrafish with mutations in mismatch repair genes develop neurofibromas and other tumors.
|
18593904 |
2008 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
Novel biallelic mutations in MSH6 and PMS2 genes: gene conversion as a likely cause of PMS2 gene inactivation.
|
17557300 |
2007 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
Medulloblastoma, acute myelocytic leukemia and colonic carcinomas in a child with biallelic MSH6 mutations.
|
17259933 |
2007 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
Our findings support a role for MSH6 in Turcot syndrome and are consistent with an autosomal recessive mode of inheritance.
|
16000562 |
2005 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
Neurofibromatosis von Recklinghausen type I phenotype and early onset of cancers in siblings compound heterozygous for mutations in MSH6.
|
16283678 |
2005 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
A homozygous MSH6 mutation in a child with café-au-lait spots, oligodendroglioma and rectal cancer.
|
15340263 |
2004 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
A homozygous germ-line mutation in the human MSH2 gene predisposes to hematological malignancy and multiple café-au-lait spots.
|
11809679 |
2002 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
Evidence for a recessive inheritance of Turcot's syndrome caused by compound heterozygous mutations within the PMS2 gene.
|
10763829 |
2000 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
Neurofibromatosis and early onset of cancers in hMLH1-deficient children.
|
9927034 |
1999 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
Turcot syndrome (disorder)
|
0.800 |
Biomarker |
CLINGEN |
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility.
|
9390556 |
1997 |