Source: CLINGEN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN Embryonic type Na+ channel β-subunit, SCN3B masks the disease phenotype of Brugada syndrome. 27677334

2016
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN Contribution of Cardiac Sodium Channel β-Subunit Variants to Brugada Syndrome. 26179811

2015
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN Is sudden unexplained nocturnal death syndrome in Southern China a cardiac sodium channel dysfunction disorder? 24529773

2014
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN Novel SCN3B mutation associated with brugada syndrome affects intracellular trafficking and function of Nav1.5. 23257389

2013
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation. 21051419

2011
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN Sudden infant death syndrome-associated mutations in the sodium channel beta subunits. 20226894

2010
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype. 20031595

2009
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties. 19351516

2009
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN Modulation of Na(v)1.5 by beta1-- and beta3-subunit co-expression in mammalian cells. 15455233

2005
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN Distinct subcellular localization of different sodium channel alpha and beta subunits in single ventricular myocytes from mouse heart. 15007009

2004
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C2748542
Disease: CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)
CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder) 		0.300 Biomarker CLINGEN The sodium channel beta-subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart. 11744748

2001