Source: CLINGEN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
CUI: C4707243
Disease: Familial thoracic aortic aneurysm and aortic dissection
Familial thoracic aortic aneurysm and aortic dissection 		0.500 Biomarker CLINGEN Smooth muscle filamin A is a major determinant of conduit artery structure and function at the adult stage. 27023351

2016
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
CUI: C4707243
Disease: Familial thoracic aortic aneurysm and aortic dissection
Familial thoracic aortic aneurysm and aortic dissection 		0.500 Biomarker CLINGEN Arterial Myogenic Activation through Smooth Muscle Filamin A. 26923587

2016
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
CUI: C4707243
Disease: Familial thoracic aortic aneurysm and aortic dissection
Familial thoracic aortic aneurysm and aortic dissection 		0.500 Biomarker CLINGEN Routine Genetic Testing for Thoracic Aortic Aneurysm and Dissection in a Clinical Setting. 26188975

2015
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
CUI: C4707243
Disease: Familial thoracic aortic aneurysm and aortic dissection
Familial thoracic aortic aneurysm and aortic dissection 		0.500 Biomarker CLINGEN Vascular and connective tissue anomalies associated with X-linked periventricular heterotopia due to mutations in Filamin A. 23032111

2013
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
CUI: C4707243
Disease: Familial thoracic aortic aneurysm and aortic dissection
Familial thoracic aortic aneurysm and aortic dissection 		0.500 Biomarker CLINGEN Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 deficient mice. 23977256

2013
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
CUI: C4707243
Disease: Familial thoracic aortic aneurysm and aortic dissection
Familial thoracic aortic aneurysm and aortic dissection 		0.500 Biomarker CLINGEN Proteomic analysis in aortic media of patients with Marfan syndrome reveals increased activity of calpain 2 in aortic aneurysms. 19720936

2009
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
CUI: C4707243
Disease: Familial thoracic aortic aneurysm and aortic dissection
Familial thoracic aortic aneurysm and aortic dissection 		0.500 Biomarker CLINGEN Filamin A (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis. 17172441

2006