DisGeNET - a database of gene-disease associations

Source: CTD_human

Disease: Alzheimer's Disease ×

Gene: A2M ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	2
Gene Symbol:	A2M

A2M

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.500

Biomarker

CTD_human

The presence of MPO-G/G and A2M-Val/Val genotypes synergistically increased the risk of AD (OR, 25.5; 95% CI, 4.65-139.75).

15023809

2004

Entrez Id:	2
Gene Symbol:	A2M

A2M

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.500

Biomarker

CTD_human

Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.

9811940

1998

Entrez Id:	2
Gene Symbol:	A2M

A2M

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.500

Biomarker

CTD_human

Alpha-2 macroglobulin is genetically associated with Alzheimer disease.

9697696

1998