DisGeNET - a database of gene-disease associations

Source: CTD_human

Disease: Malignant tumor of colon ×

Gene: NOTCH1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	4851
Gene Symbol:	NOTCH1

NOTCH1

CUI:	C0007102
Disease:	Malignant tumor of colon

Malignant tumor of colon

0.360

Biomarker

CTD_human

In summary, colon cancer cells may up-regulate Notch-1 as a protective mechanism in response to chemotherapy.

2009