Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4544
Gene Symbol: MTNR1B
MTNR1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.500 Biomarker CTD_human We observed allele-specific differences in NEUROD1 binding in islet-derived cells, consistent with evidence that the T2D risk allele increases islet MTNR1B expression. 26551672

2015
Entrez Id: 4544
Gene Symbol: MTNR1B
MTNR1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.500 Biomarker CTD_human This study establishes a firm functional link between MTNR1B and T2D risk. 22286214

2012
Entrez Id: 4544
Gene Symbol: MTNR1B
MTNR1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.500 Biomarker CTD_human Variants in MTNR1B influence fasting glucose levels. 19060907

2009
Entrez Id: 4544
Gene Symbol: MTNR1B
MTNR1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.500 Biomarker CTD_human A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. 19060909

2009
Entrez Id: 4544
Gene Symbol: MTNR1B
MTNR1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.500 Biomarker CTD_human Given the increased expression of MTNR1B in individuals at risk of T2D, the pathogenic effects are likely exerted via a direct inhibitory effect on beta cells. 19060908

2009