Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.400 Biomarker CTD_human Collectively, these studies indicate that podocyte VEGF-A regulates alpha(V)beta(3) integrin signaling in the glomerulus, and that podocyte VEGF knockdown disrupts alpha(V)beta(3) integrin activity via decreased VEGFR2 signaling, thereby damaging the three layers of the glomerular filtration barrier, causing proteinuria and acute renal failure. 22808199

2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.400 Therapeutic CTD_human Collectively, these studies indicate that podocyte VEGF-A regulates alpha(V)beta(3) integrin signaling in the glomerulus, and that podocyte VEGF knockdown disrupts alpha(V)beta(3) integrin activity via decreased VEGFR2 signaling, thereby damaging the three layers of the glomerular filtration barrier, causing proteinuria and acute renal failure. 22808199

2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.400 Therapeutic CTD_human Whether upregulation of VEGF by a combination of MSC and VEGF gene transfer could enhance the protective effect of MSC in AKI is not clear. 20943766

2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.400 Biomarker CTD_human Whether upregulation of VEGF by a combination of MSC and VEGF gene transfer could enhance the protective effect of MSC in AKI is not clear. 20943766

2011