Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025202
Disease: melanoma
melanoma 		0.700 Biomarker CTD_human Considering the antitumor activity of benzothiazolic derivatives, this study aimed to demonstrate the action of benzothiazolic (E)-2-((2-(benzo[d]thiazol-2-yl)hydrazono)methyl)-4-nitrophenol (AFN01) against three established human melanoma cell lines that recapitulate the molecular landscape of the disease in terms of its genetic alterations and mutations, such as the TP53, NRAS and B-RAF genes. 29574239

2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025202
Disease: melanoma
melanoma 		0.700 Biomarker CTD_human Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. 22842228

2012
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025202
Disease: melanoma
melanoma 		0.700 Biomarker CTD_human We detected high homeodomain-interacting protein kinase-2 level in melanomas-expressing mutant p53. 21691232

2011
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0025202
Disease: melanoma
melanoma 		0.700 Biomarker CTD_human The DW1/2 compound was barely able to induce cell death in melanoma cells with p53 mutations, further confirming the requirement for p53-WT in the cytotoxic effects of the GSK3beta inhibition. 17210701

2007