Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Anti-t-PA antibodies in acute myocardial infarction after thrombolysis with rt-PA. 20122609

2010

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human The patients with myocardial infarction after administration of alteplase had statistically significantly higher coronary flow (TIMI-3), 72.5% as compared to the patients who received streptokinase, 39.2%. 19341228

2009

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Key role of tissue plasminogen activator in neurovascular coupling. 18195371

2008

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Predictors of intracranial hemorrhage with fibrinolytic therapy in unselected community patients: a report from the FASTRAK II project. 15215796

2004

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Cocaine-induced coronary thrombosis and acute myocardial infarction. 15301905

2004

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Angioplasty in acute myocardial infarction after low-dose alteplase and abciximab in transferred patients. A comparison with primary angioplasty on site. 12848087

2003

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Spinal epidural hematoma following tissue plasminogen activator and heparinization for acute myocardial infarction. 12227717

2002

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Lanoteplase plasma clearance averaged 3 L/h (50 ml/min), whereas the mean plasma clearance of approximately 24 L/h (400 ml/min) for alteplase approaches hepatic blood flow following acute myocardial infarction. 12074692

2002

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human New heparin dosing recommendations for patients with acute coronary syndromes. 11382373

2001

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Randomized comparison of enoxaparin, a low-molecular-weight heparin, with unfractionated heparin adjunctive to recombinant tissue plasminogen activator thrombolysis and aspirin: second trial of Heparin and Aspirin Reperfusion Therapy (HART II). 11489769

2001

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Paraplegia subsequent to administration of tissue plasminogen activator and intravenous heparin following myocardial infarction--a case report. 10914357

2000

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Spontaneous compartment syndrome after thrombolytic therapy. 10645301

1999

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Cocaine induced myocardial infarction. 10505926

1999

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Ischemic cerebral infarction after rt-PA and heparin therapy for acute myocardial infarction. The TIMI-II pilot and randomized clinical trial combined experience. 9183334

1997

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Changes in interstitial collagen metabolism during acute myocardial infarction treated with streptokinase or tissue plasminogen activator. 8554022

1996

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Comparisons of characteristics and outcomes among women and men with acute myocardial infarction treated with thrombolytic therapy. GUSTO-I investigators. 8598594

1996

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Current issues concerning thrombolytic therapy for acute myocardial infarction. 7775709

1995

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Thrombolytic treatment and proteinuria. 7488445

1995

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Individual risk assessment for intracranial haemorrhage during thrombolytic therapy. 7902905

1994

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human [New substances and dosages for thrombolysis in acute myocardial infarct]. 8328192

1993

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human An overview of the patency and stroke rates following thrombolysis with streptokinase, alteplase, and anistreplase used to treat an acute myocardial infarction. 10171637

1993

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Severe acute myocardial infarction during a staphylococcal septicemia with meningoencephalitis. A possible contraindication to thrombolytic treatment. 1430592

1992

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human The frequency and severity of adverse effects resulting from the administration of streptokinase and alteplase were determined in 126 consecutive patients who received standard dosages of these agents for the treatment of acute myocardial infarction. 1492007

1992

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Intracerebral hemorrhage, cerebral infarction, and subdural hematoma after acute myocardial infarction and thrombolytic therapy in the Thrombolysis in Myocardial Infarction Study. Thrombolysis in Myocardial Infarction, Phase II, pilot and clinical trial. 1899364

1991

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Therapeutic CTD_human Cardiac tamponade early after thrombolysis for acute myocardial infarction: a rare but not reported hemorrhagic complication. 1898952

1991