Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0028754
Disease: Obesity
Obesity 		0.600 Biomarker CTD_human Obese subjects had increased levels of oxidative damage: 4-HNE (+37%; P0.03) and PC (+63%; P0.02); evidence of increased adaptive response to oxidative stress because of elevated levels of copper/zinc SOD (Cu/ZnSOD) protein content (+84%; P0.01); increased markers of inflammation: CRP (+737%; P0.0001) and IL-6 (+85%; P0.03), and these correlated with increased markers of obesity; and increased leptin (+262%; P0.0001) with lower adiponectin (-27%; P0.01) levels vs lean controls. 24042701

2013
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0028754
Disease: Obesity
Obesity 		0.600 Biomarker CTD_human The chronic inflammatory response caused by obesity and enhanced production of IL-6 and TNF may also increase the risk of other cancers. 20141834

2010