Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 48
Gene Symbol: ACO1
ACO1
CUI: C0003130
Disease: Anoxia
Anoxia 		0.020 Biomarker LHGDN Further density gradient fractionation of HepG2 membranes revealed that hypoxia caused an increase in total membrane IRP1, with a shift in the membrane-bound fraction from Golgi to an endoplasmic reticulum (ER)-enriched fraction. 17200797

2007
Entrez Id: 48
Gene Symbol: ACO1
ACO1
CUI: C0003130
Disease: Anoxia
Anoxia 		0.020 Biomarker LHGDN Here we describe the consequences of IRP regulation and show that iron homeostasis is regulated in 2 phases during hypoxia: an early phase where IRP1 RNA-binding activity decreases and iron uptake and Ft synthesis increase, and a late phase where IRP2 RNA-binding activity increases and iron uptake and Ft synthesis decrease. 12855587

2003