Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4056
Gene Symbol: LTC4S
LTC4S
CUI: C0004096
Disease: Asthma
Asthma 		0.100 Biomarker LHGDN No association was detected between the -444A> C LTC4S polymorphism and the asthma phenotype. 17153879

2006
Entrez Id: 4056
Gene Symbol: LTC4S
LTC4S
CUI: C0004096
Disease: Asthma
Asthma 		0.100 GeneticVariation LHGDN The leukotriene C4 synthase (A-444C) promoter polymorphism is associated with the severity of exercise-induced asthma in Korean children. 16675353

2006
Entrez Id: 4056
Gene Symbol: LTC4S
LTC4S
CUI: C0004096
Disease: Asthma
Asthma 		0.100 GeneticVariation LHGDN We studied 61 patients with asthma and/or atopy and 129 to 157 newborn controls for the -403 RANTES, -28 RANTES, and -1055 IL-13 SNPs, as well as 47 patients and 60 newborn controls for the -444 LTC4S SNP. 16024972

2005
Entrez Id: 4056
Gene Symbol: LTC4S
LTC4S
CUI: C0004096
Disease: Asthma
Asthma 		0.100 Biomarker LHGDN The density of LTC4S-positive mast cells correlated, moreover, with both the reduction in lung function and the degree of reversibility in treated asthma. 12816731

2003
Entrez Id: 4056
Gene Symbol: LTC4S
LTC4S
CUI: C0004096
Disease: Asthma
Asthma 		0.100 GeneticVariation LHGDN Effect of montelukast on time-course of exhaled nitric oxide in asthma: influence of LTC4 synthase A(-444)C polymorphism. 14520724

2003
Entrez Id: 4056
Gene Symbol: LTC4S
LTC4S
CUI: C0004096
Disease: Asthma
Asthma 		0.100 GeneticVariation LHGDN We conclude that LTC(4) S genotype is predictive of the clinical response to a cysLT(1) antagonist, pranlukast, in Japanese patients with moderate asthma. 12360108

2002