Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0004096
Disease: Asthma
Asthma
0.300 Biomarker LHGDN Clinical data show that mixed COX-1/COX-2 inhibitors such as aspirin, but not COX-2 selective inhibitors such as rofecoxib, induce bronchoconstriction and asthma in sensitive individuals. 18753249

2008

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0004096
Disease: Asthma
Asthma
0.300 GeneticVariation LHGDN To evaluate the frequencies of COX-2 SNPs in an Australian Caucasian population, and determine potential associations between common COX-2 promoter SNPs and asthma, asthma severity and aspirin-intolerant asthma (AIA). 18489027

2008

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0004096
Disease: Asthma
Asthma
0.300 GeneticVariation LHGDN Among the four SNPs, only PTGS2.8473 showed significant association with asthma (P = 0.034) and atopy (P = 0.005 when compared with non-atopic controls; P = 0.023 with all controls). 17573729

2007