DisGeNET - a database of gene-disease associations

Gene: AKT2 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	208
Gene Symbol:	AKT2

AKT2

CUI:	C0007137
Disease:	Squamous cell carcinoma

Squamous cell carcinoma

0.020

AlteredExpression

LHGDN

In squamous cell carcinomas (SCC), AKT1 down-regulation is also common, consistent with a viral influence, whereas AKT2 up-regulation is widespread.

2007