DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Squamous cell carcinoma ×

Gene: ADAM17 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	6868
Gene Symbol:	ADAM17

ADAM17

CUI:	C0007137
Disease:	Squamous cell carcinoma

Squamous cell carcinoma

0.060

Biomarker

LHGDN

TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells.

2003