Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2697
Gene Symbol: GJA1
GJA1
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.050 AlteredExpression LHGDN Cx43 expression and cell-to-cell communication increased in response to high glucose and may protect the collecting duct from renal damage associated with more established diabetic nephropathy. 16684925

2006

Entrez Id: 2697
Gene Symbol: GJA1
GJA1
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.050 AlteredExpression LHGDN These results demonstrate for the first time that downregulation of Cx43 expression by high glucose promotes the senescence of GMC, which may be involved in the pathogenesis of diabetic nephropathy. 16675599

2006