DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Chronic Lymphocytic Leukemia ×

Gene: MCL1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	4170
Gene Symbol:	MCL1

MCL1

CUI:	C0023434
Disease:	Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

0.100

AlteredExpression

LHGDN

Low MCL-1 mRNA expression correlates with prolonged survival in B-cell chronic lymphocytic leukemia.

18046444

2008

Entrez Id:	4170
Gene Symbol:	MCL1

MCL1

CUI:	C0023434
Disease:	Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

0.100

Biomarker

LHGDN

Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

15728130

2005