DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Leukemia, Myelocytic, Acute ×

Gene: CDKN2B ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	1030
Gene Symbol:	CDKN2B

CDKN2B

CUI:	C0023467
Disease:	Leukemia, Myelocytic, Acute

Leukemia, Myelocytic, Acute

0.100

Biomarker

LHGDN

These results suggest perturbed modifications of histone H3 around the p15 CpG island region in AML.

17074388

2007

Entrez Id:	1030
Gene Symbol:	CDKN2B

CDKN2B

CUI:	C0023467
Disease:	Leukemia, Myelocytic, Acute

Leukemia, Myelocytic, Acute

0.100

PosttranslationalModification

LHGDN

Methylation of p15 was less common in t-AML of subtype M5 than in other FAB subtypes (P=0.03).

12970781

2003