DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Myeloid Leukemia ×

Gene: IL18 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	3606
Gene Symbol:	IL18

IL18

CUI:	C0023470
Disease:	Myeloid Leukemia

Myeloid Leukemia

0.010

AlteredExpression

LHGDN

We postulate that IL-18 may in part play a role in the clinical aggressiveness of human myeloid leukemia by stimulating MMP-9 production.

2004