Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.100 AlteredExpression LHGDN Breast cancer metastasis suppressor 1 inhibits SDF-1alpha-induced migration of non-small cell lung cancer by decreasing CXCR4 expression. 18502034

2008
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.100 AlteredExpression LHGDN Nuclear expression of CXCR4 in tumor cells of non-small cell lung cancer is correlated with lymph node metastasis. 18701133

2008
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.100 AlteredExpression LHGDN Involvement of matrix metalloproteinase-9 in stromal cell-derived factor-1/CXCR4 pathway of lung cancer metastasis. 17916907

2008
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.100 Biomarker LHGDN CD4+CXCR4highCD69+ T cells accumulate in lung adenocarcinoma. 17082613

2006
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.100 AlteredExpression LHGDN Differential expression of CXCR4 is associated with the metastatic potential of human non-small cell lung cancer cells. 16322285

2005
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.100 AlteredExpression LHGDN Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha. 15802268

2005
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.100 Biomarker LHGDN Stromal-derived factor-1alpha/CXCL12-CXCR 4 axis is involved in the dissemination of NSCLC cells into pleural space. 14672915

2004
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.100 Biomarker LHGDN Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: pattern of expression and correlation with outcome. 15033669

2004