Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.700 Biomarker LHGDN Associations of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC Class II alleles in systemic lupus erythematosus. 18085741

2008

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.700 AlteredExpression LHGDN HLA-DRB1 gene is a mayor factor for development of SLE in Latin Americans. 18295738

2008

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.700 GeneticVariation LHGDN The SLE patients with HLA-DRB1 * 15 and controls were analyzed for either the gene originated from the paternal or the maternal side. 14748996

2003

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.700 GeneticVariation LHGDN A highly significant increase in the frequency of DRB1*1502 and DQB1*0501 was found in SLE patients compared with normal controls. 12028537

2002

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
0.700 GeneticVariation LHGDN We conclude that HLA class II haplotypes containing DRB1 and DQB1 alleles are strong risk factors for human SLE. 12145745

2002