Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3685
Gene Symbol: ITGAV
ITGAV
CUI: C0025202
Disease: melanoma
melanoma 		0.100 AlteredExpression LHGDN Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets. 18211678

2008
Entrez Id: 3685
Gene Symbol: ITGAV
ITGAV
CUI: C0025202
Disease: melanoma
melanoma 		0.100 AlteredExpression LHGDN We have previously shown an increase in pp(60c-Src) kinase activity associated with integrin alpha(v)beta3 in melanoma cells (M21) treated with soluble OPN. pp(60c-Src) kinase activity was not observed in melanoma cells expressing alpha(v) that lacks the cytoplasmic domain (alpha(v)995). 16631740

2006
Entrez Id: 3685
Gene Symbol: ITGAV
ITGAV
CUI: C0025202
Disease: melanoma
melanoma 		0.100 Biomarker LHGDN alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen. 15998788

2005
Entrez Id: 3685
Gene Symbol: ITGAV
ITGAV
CUI: C0025202
Disease: melanoma
melanoma 		0.100 AlteredExpression LHGDN Interaction of human Thy-1 (CD 90) with the integrin alphavbeta3 (CD51/CD61): an important mechanism mediating melanoma cell adhesion to activated endothelium. 15897908

2005
Entrez Id: 3685
Gene Symbol: ITGAV
ITGAV
CUI: C0025202
Disease: melanoma
melanoma 		0.100 Biomarker LHGDN CEACAM1 enhances invasion and migration of melanocytic and melanoma cells. 15509546

2004
Entrez Id: 3685
Gene Symbol: ITGAV
ITGAV
CUI: C0025202
Disease: melanoma
melanoma 		0.100 Biomarker LHGDN Integrin alphav-mediated inactivation of p53 controls a MEK1-dependent melanoma cell survival pathway in three-dimensional collagen. 15557124

2004
Entrez Id: 3685
Gene Symbol: ITGAV
ITGAV
CUI: C0025202
Disease: melanoma
melanoma 		0.100 AlteredExpression LHGDN We tested whether integrin alpha v beta 3 supports metastasis of human melanoma cells when injected into the bloodstream of immune deficient mice. 12198771

2002