Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0025202
Disease: melanoma
melanoma 		0.100 Biomarker LHGDN Expression of collagenase-1 (MMP-1) promotes melanoma growth through the generation of active transforming growth factor-beta. 17625450

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0025202
Disease: melanoma
melanoma 		0.100 AlteredExpression LHGDN These results demonstrate that TGF-beta1 suppresses not only the acquisition but also expression of effector function on human memory CD8 T cells and tumor-infiltrating lymphocytes reactive against melanoma, suggesting that TGF-beta1-mediated suppression can hinder the therapeutic benefits of vaccination, as well as immunotherapy in cancer patients. 15843517

2005