Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.400 Biomarker LHGDN APOE epsilon 4 allele is associated with cognitive impairment in patients with multiple sclerosis. 17460153

2008
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.400 GeneticVariation LHGDN Studies examining the epsilon4 allele of the APOE gene as a factor affecting the severity of multiple sclerosis (MS) have yielded conflicting results. 17294608

2007
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.400 GeneticVariation LHGDN To investigate the association between apolipoprotein E (Apo E) genotype in multiple sclerosis (MS) and acute monosymptomatic optic neuritis (ON) in a genetically homogeneous population with a high frequency of the Apo epsilon4 allele. 16193886

2005
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.400 GeneticVariation LHGDN The telltale scan: APOE epsilon4 in multiple sclerosis. 15157846

2004
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.400 Biomarker LHGDN Apolipoprotein E (APOE)-epsilon4 has been associated with an unfavorable course of multiple sclerosis (MS). 15048896

2004
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.400 GeneticVariation LHGDN An analysis of disease progression in 614 patients with MS from 379 families indicated that APOE-4 carriers are more likely to be affected with severe disease (P=.03), whereas a higher proportion of APOE-2 carriers exhibit a mild disease course (P=.02). 11836653

2002
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.400 GeneticVariation LHGDN Apolipoprotein E epsilon 4 is associated with rapid progression of multiple sclerosis. 11552016

2001