Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.300 AlteredExpression LHGDN Increase of CD4+TNF{alpha}+IL-2-T cells in cerebrospinal fluid of multiple sclerosis patients. 18755820

2009
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.300 Biomarker LHGDN Resting plasma TNF-alpha tended to be higher in MS compared with controls throughout the study (P = 0.08). 18388249

2008
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.300 GeneticVariation LHGDN IL-1, IL-1R and TNFalpha gene polymorphisms in Iranian patients with multiple sclerosis. 18322311

2008
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.300 GeneticVariation LHGDN Tumor necrosis factor-alpha-308 gene polymorphism in Croatian and Slovenian multiple sclerosis patients. 17268200

2007
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.300 GeneticVariation LHGDN Profile of cytokine gene polymorphisms in Iranian multiple sclerosis patients. 17439892

2007
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.300 GeneticVariation LHGDN GFAP, a measure of astrocytosis, was the only cytological marker that was consistently elevated in the MS NAWM, suggesting that TNF-alpha may have been derived from astrocytes. 17079667

2006
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.300 Biomarker LHGDN We have concluded that soluble proteins of TNF-alpha, IL-6 and sIL-6R gp80 assayed by monoclonal antibodies-based ELISAs could not serve as markers of the MS activity. 12445803

2002
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.300 AlteredExpression LHGDN BDI sum scores (2,9 fold) and the expression levels of tumor necrosis factor-alpha (TNF-alpha; 4 fold), interferon-gamma (IFN-gamma; 4,6 fold) and interleukin-10 (IL-10; 6,1 fold) mRNA were increased in MS patients during an acute attack compared to age and sex matched healthy controls. 12084660

2002