Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.070 AlteredExpression LHGDN Identification of an inducible factor secreted by pancreatic cancer cell lines that stimulates the production of fucosylated haptoglobin in hepatoma cells. 18951869

2008
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.070 GeneticVariation LHGDN Association of IL-6 gene polymorphisms with cachexia susceptibility and survival time of patients with pancreatic cancer. 18469355

2008
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.070 Biomarker LHGDN Because insulin-like growth factor-I receptor (IGF-IR) and signal transducer and activator of transcription 3 (STAT3) signaling pathways are implicated in the progression of pancreatic cancer, we hypothesized that blocking Hsp90 with geldanamycin derivates [17-allylamino-geldanamycin (17-AAG), 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG)] would impair IGF-I- and interleukin-6-mediated signaling and thus reduce pancreatic tumor growth and angiogenesis in vivo. 17975158

2007
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.070 AlteredExpression LHGDN Role of mononuclear cells and inflammatory cytokines in pancreatic cancer-related cachexia. 16115919

2005
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.070 Biomarker LHGDN GSK3 and PKB/Akt are associated with integrin-mediated regulation of PTHrP, IL-6 and IL-8 expression in FG pancreatic cancer cells. 15609321

2005