Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
0.100 GeneticVariation LHGDN Our aim was to examine the role of the sex hormone-binding globulin (SHBG) and androgen receptor (AR) gene polymorphisms, in the phenotypic expression of PCOS. 18192296

2008

Entrez Id: 6462
Gene Symbol: SHBG
SHBG
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
0.100 Biomarker LHGDN The aim of this study was to examine whether the sex hormone binding globulin (SHBG)(TAAAA)n and the cytochrome P450, family 19 (CYP19)(TTTA)n polymorphisms, known to influence sex hormone-binding globulin (SHBG) levels and aromatase activity respectively, play a synergistic role in the development of PCOS. 18505907

2008

Entrez Id: 6462
Gene Symbol: SHBG
SHBG
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
0.100 GeneticVariation LHGDN In conclusion, the D327N polymorphism of the SHBG gene does not influence susceptibility to PCOS. 17258903

2007

Entrez Id: 6462
Gene Symbol: SHBG
SHBG
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
0.100 Biomarker LHGDN Low sex hormone-binding globulin is associated with low high-density lipoprotein cholesterol and metabolic syndrome in women with PCOS. 16757555

2006

Entrez Id: 6462
Gene Symbol: SHBG
SHBG
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
0.100 Biomarker LHGDN The biological variation of testosterone and sex hormone-binding globulin (SHBG) in polycystic ovarian syndrome: implications for SHBG as a surrogate marker of insulin resistance. 12679434

2003

Entrez Id: 6462
Gene Symbol: SHBG
SHBG
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
0.100 AlteredExpression LHGDN Our aim was to investigate the possible association of the functional (TAAAA)n polymorphism in the promoter of the SHBG gene with PCOS and its relation to SHBG levels. 14671199

2003